MK-8617
Product Specifications
CAS Number
1187990-87-9
Target
HIF
Applications
Angiogenesis
Smiles
COC1=CC=C (C=C1) C (C2=CC=C (C=C2) OC) NC (=O) C3=CN=C (NC3=O) C4=NN=CC=C4
Molecular Formula
C24H21N5O4
Additionnal Information
MK-8617 is an orally active pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1, 2, 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.
Storage Conditions
2 years -80 in solvent
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