Troglitazone

Product Specifications

CAS Number

97322-87-7

Synonyms

CS-045, Romglizone

Target

PPAR

Applications

DNA Damage/DNA Repair

Smiles

CC1=C (C2=C (CCC (O2) (C) COC3=CC=C (C=C3) CC4C (=O) NC (=O) S4) C (=C1O) C) C

Molecular Formula

C24H27NO5S

Additionnal Information

Troglitazone is a potent agonist for the peroxisome proliferator-activated receptor- (PPAR) that is a ligand activated transcription factor regulating cell differentiation and growth. Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells. Troglitazone prevents RSL3-induced ferroptosis and lipid peroxidation in Pfa1 cells.