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10074-G5

Product Specifications

CAS Number

413611-93-5

Target

Myc

Applications

Apoptosis

Smiles

C1=CC=C (C=C1) C2=CC=CC=C2NC3=CC=C (C4=NON=C34) [N+] (=O) [O-]

Molecular Formula

C18H12N4O3

Additionnal Information

10074-G5 is a c-Myc inhibitor that binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 μM), thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (IC50 = 146 μM) .

Storage Conditions

2 years -80 in solvent

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