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RRx-001

Product Specifications

CAS Number

925206-65-1

Target

Dehydrogenase

Applications

Metabolism

Smiles

C1C (CN1C (=O) CBr) ([N+] (=O) [O-]) [N+] (=O) [O-]

Molecular Formula

C5H6BrN3O5

Additionnal Information

RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity. It inhibits glucose 6-phosphate dehydrogenase (G6PD) in human tumor cells, binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 triggers apoptosis and exhibits anticancer activity.RRx-001 is also a downregulator of the CD47- SIRPα checkpoint pathway.

Storage Conditions

2 years -80 in solvent

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