KRIBB11
Product Specifications
CAS Number
342639-96-7
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Smiles
CNC1=NC (=C (C=C1) [N+] (=O) [O-]) NC2=CC3=C (C=C2) NN=C3
Molecular Formula
C13H12N6O2
Additionnal Information
KRIBB11 abolishes the heat shock-induced luciferase activity with an IC50 of 1.2 μM. It is an inhibitor of the transcription factor Heat Shock Factor 1 (HSF1) . KRIBB11 induces growth arrest and apoptosis.
Storage Conditions
2 years -80 in solvent
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