Eltanexor (KPT-8602)
Product Specifications
CAS Number
1642300-52-4
Synonyms
ONO-7706, ATG-016
Target
CRM1
Applications
Transmembrane Transporters
Smiles
C1=C (C=C (C=C1C (F) (F) F) C (F) (F) F) C2=NN (C=N2) C=C (C3=CN=CN=C3) C (=O) N
Molecular Formula
C17H10F6N6O
Additionnal Information
Eltanexor (KPT-8602, ONO-7706, ATG-016) is a second-generation, orally bioavailable XPO1 (also known as CRM1) inhibitor with IC50 values of 20−211 nM in 10 AML lines after 3 days exposure.
Storage Conditions
2 years -80 in solvent
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