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NCB-0846

Product Specifications

CAS Number

1792999-26-8

Target

Wnt/beta-catenin

Applications

Cytoskeletal Signaling

Smiles

C1CC (CCC1O) OC2=CC=CC3=CN=C (N=C32) NC4=CC5=C (C=C4) N=CN5

Molecular Formula

C21H21N5O2

Additionnal Information

NCB-0846 is a novel, orally small-molecule Wnt inhibitor that inhibits TNIK (TRAF2 and NCK-Interacting Kinase, MAP4K7) with an IC50 value of 21 nM.

Storage Conditions

2 years -80 in solvent

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