ND646
Product Specifications
CAS Number
1434639-57-2
Target
Acetyl-CoA carboxylase
Applications
Metabolism
Smiles
COC1=CC=CC=C1C (CN2C (=O) N (C (=O) C3=C2SC (=C3C) C4=NC=CO4) C (C) (C) C (N) =O) OC5CCOCC5
Molecular Formula
C28H32N4O7S
Additionnal Information
ND-646 is an allosteric inhibitor of the ACC (Acetyl-coA carboxylase) enzymes that prevents ACC subunit dimerization to suppress fatty acid synthesis with IC50 of 3.5 nM and 4.1 nM for hACC1 and hACC2, respectively.
Storage Conditions
3 years -20°C powder
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