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AZD0156

Product Specifications

CAS Number

1821428-35-6

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

CN1C2=CN=C3C=CC (=CC3=C2N (C1=O) C4CCOCC4) C5=CN=C (C=C5) OCCCN (C) C

Molecular Formula

C26H31N5O3

Additionnal Information

AZD0156 is a potent and selective inhibitors of ATM kinase, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD0156 prevents DNA damage checkpoint activation, disrupts DNA damage repair, induces tumor cell apoptosis, and leads to cell death of ATM-overexpressing tumor cells.

Storage Conditions

2 years -80 in solvent

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