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GSK2193874

Product Specifications

CAS Number

1336960-13-4

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

C1CCN (CC1) C2CCN (CC2) CC3=C (C4=C (C=C (C=C4) Br) N=C3C5=CC (=CC=C5) C (F) (F) F) C (=O) NC6 (CC6) C7=CC=CC=C7

Molecular Formula

C37H38BrF3N4O

Additionnal Information

GSK2193874 is an orally active, potent, and selective blocker of transient receptor potential vanilloid 4 (TRPV4) with IC50 values of 0.04 and 0.002 μM for hTRPV4 and rTRPV4, respectively.

Storage Conditions

2 years -80 in solvent

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