UNC3866
Product Specifications
CAS Number
1872382-47-2
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CCN (CC) CCCCC (C (=O) NC (CO) C (=O) OC) NC (=O) C (CC (C) C) NC (=O) C (C) NC (=O) C (CC1=CC=CC=C1) NC (=O) C2=CC=C (C=C2) C (C) (C) C
Molecular Formula
C43H66N6O8
Additionnal Information
UNC3866 is a potent antagonist of the methyllysine (Kme) reading function of the Polycomb CBX and CDY families of chromodomains. UNC3866 binds the chromodomains of CBX4 and CBX7 most potently, with a K (d) of ∼100 nM for each, and is 6- to 18-fold selective as compared to seven other CBX and CDY chromodomains.
Storage Conditions
2 years -80 in solvent
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