WNK463

Product Specifications

CAS Number

2012607-27-9

Target

Serine/threonin kinase

Applications

Cell Cycle

Smiles

CC (C) (C) NC (=O) C1=CN=CN1C2CCN (CC2) C3=NC=C (C=C3) C4=NN=C (O4) C (F) (F) F

Molecular Formula

C21H24F3N7O2

Additionnal Information

WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4) with IC50 of 5nM, 1nM, 6nM, and 9nM.

Storage Conditions

2 years -80 in solvent

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