APS-2-79 HCl
Product Specifications
CAS Number
2002381-31-7
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=CC (=C1) OC2=CC=CC=C2) NC3=NC=NC4=CC (=C (C=C43) OC) OC.Cl
Molecular Formula
C23H21N3O3.HCl
Additionnal Information
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK. IC50=120 ± 23 nM.
Storage Conditions
2 years -80 in solvent
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