BMS-935177
Product Specifications
CAS Number
1231889-53-4
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=CC=C1N2C=NC3=CC=CC=C3C2=O) C4=C5C6=C (C=C (C=C6) C (C) (C) O) NC5=C (C=C4) C (=O) N
Molecular Formula
C31H26N4O3
Additionnal Information
BMS-935177 is a potent, reversible Bruton's Tyrosine Kinase (BTK) inhibitor with an IC50 value of 2.8 nM and demonstrates good kinase selectivity. It is more potent against BTK than other kinase, including the other Tec family kinases (TEC, BMX, ITK, and TXK) over which the compound is between 5- and 67-fold selective.
Storage Conditions
2 years -80 in solvent
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