Kobe0065
Product Specifications
CAS Number
436133-68-5
Target
Ras
Applications
Apoptosis
Smiles
CC1=C (C=C (C=C1) NC (=S) NNC2=C (C=C (C=C2[N+] (=O) [O-]) C (F) (F) F) [N+] (=O) [O-]) Cl
Molecular Formula
C15H11ClF3N5O4S
Additionnal Information
Kobe0065 is an H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.
Storage Conditions
2 years -80 in solvent
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