HA15
Product Specifications
CAS Number
1609402-14-3
Target
HSP (HSP90)
Applications
Cytoskeletal Signaling
Smiles
CC (=O) NC1=NC (=CS1) C2=CC (=CC=C2) NS (=O) (=O) C3=CC=CC4=C3C=CC=C4N (C) C
Molecular Formula
C23H22N4O3S2
Additionnal Information
HA15 is a molecule that targets specifically HSPA5 (Heat shock 70kDa protein 5) also known as BiP (Immunoglobulin heavy-chain-binding protein) or Grp78 (glucose-regulated protein 78) . HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
Storage Conditions
2 years -80 in solvent
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