Tomivosertib (eFT-508)
Product Specifications
CAS Number
1849590-01-7
Target
MNK
Applications
MAPK
Smiles
CC1=C2C (=O) NC3 (N2C (=O) C (=C1) NC4=NC=NC (=C4) N) CCCCC3
Molecular Formula
C17H20N6O2
Additionnal Information
Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K7568505 3x 1.0 µg
Kat8 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details 
APR09085G 0.05mg
Monoclonal PHAP1 / ANP32A Antibody (clone 2G11-4A5), Clone: 2G11-4A5
Sign In for Pricing
View Details