Tomivosertib (eFT-508)
Product Specifications
CAS Number
1849590-01-7
Target
MNK
Applications
MAPK
Smiles
CC1=C2C (=O) NC3 (N2C (=O) C (=C1) NC4=NC=NC (=C4) N) CCCCC3
Molecular Formula
C17H20N6O2
Additionnal Information
Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.
Storage Conditions
2 years -80 in solvent
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