Luvixasertib (CFI-402257)
Product Specifications
CAS Number
1610759-22-2
Synonyms
Luvixasertib
Target
Serine/threonin kinase
Applications
Cell Cycle
Molecular Formula
C28H30N6O3
Additionnal Information
Luvixasertib (CFI-402257) is an inhibitor of threonine tyrosine kinase (TTK) with IC50 of 1.7 nM and Ki of 0.1 nM, respectively. It is a potential therapeutic for treating hepatocellular carcinoma that works directly by inhibiting cell-cycle checkpoints in cancer cells and indirectly by mobilizing immune cells from the tumor microenvironment.
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