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Luvixasertib (CFI-402257)

Product Specifications

CAS Number

1610759-22-2

Synonyms

Luvixasertib

Target

Serine/threonin kinase

Applications

Cell Cycle

Molecular Formula

C28H30N6O3

Additionnal Information

Luvixasertib (CFI-402257) is an inhibitor of threonine tyrosine kinase (TTK) with IC50 of 1.7 nM and Ki of 0.1 nM, respectively. It is a potential therapeutic for treating hepatocellular carcinoma that works directly by inhibiting cell-cycle checkpoints in cancer cells and indirectly by mobilizing immune cells from the tumor microenvironment.

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