HPI-4 (Ciliobrevin A)
Product Specifications
CAS Number
302803-72-1
Synonyms
Hedgehog Pathway Inhibitor 4
Target
Hedgehog/Smoothened
Applications
Stem Cells & Wnt
Smiles
C1=CC=C2C (=C1) C (=O) NC (=N2) C (=C (C3=C (C=C (C=C3) Cl) Cl) O) C#N
Molecular Formula
C17H9Cl2N3O2
Additionnal Information
HPI-4 (Ciliobrevin A, Hedgehog Pathway Inhibitor 4) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh) -induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.
Storage Conditions
2 years -80 in solvent
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