Brigatinib
Product Specifications
CAS Number
1197953-54-0
Synonyms
AP26113
Target
ALK
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C2CCN (CC2) C3=CC (=C (C=C3) NC4=NC=C (C (=N4) NC5=CC=CC=C5P (=O) (C) C) Cl) OC
Molecular Formula
C29H39ClN7O2P
Additionnal Information
Brigatinib is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.
Storage Conditions
2 years -80 in solvent
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