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Brigatinib

Product Specifications

CAS Number

1197953-54-0

Synonyms

AP26113

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C2CCN (CC2) C3=CC (=C (C=C3) NC4=NC=C (C (=N4) NC5=CC=CC=C5P (=O) (C) C) Cl) OC

Molecular Formula

C29H39ClN7O2P

Additionnal Information

Brigatinib is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits IGF-1R, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.

Storage Conditions

2 years -80 in solvent

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