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INT-777

Product Specifications

CAS Number

1199796-29-6

Synonyms

S-EMCA

Target

GPCR19

Applications

GPCR & G Protein

Smiles

CCC1C2CC (CCC2 (C3CC (C4 (C (C3C1O) CCC4C (C) CC (C) C (=O) O) C) O) C) O

Molecular Formula

C27H46O5

Additionnal Information

INT-777 (S-EMCA) is a potent and selective agonist of TGR5 (GPCR19) with EC50 of 0.18 μM, 3.9 μM and 1.45 μM for TGR5, TGR5 (N76A) and TGR5 (Y89F) respectively.

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