Upadacitinib

Product Specifications

CAS Number

1310726-60-3

Synonyms

ABT-494

Target

JAK

Applications

Angiogenesis

Smiles

CCC1CN (CC1C2=CN=C3N2C4=C (NC=C4) N=C3) C (=O) NCC (F) (F) F

Molecular Formula

C17H19F3N6O

Additionnal Information

Upadacitinib is a selective JAK1 inhibitor which demonstrates activity against JAK1 (0.045 μM) and JAK2 (0.109 μM), with > 40 fold selectivity over JAK3 (2.1 μM) and 100 fold selectivity over TYK2 (4.7 μM) as compared to JAK1.

Storage Conditions

3 years -20°C powder

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