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ON123300

Product Specifications

CAS Number

1357470-29-1

Target

CDK

Applications

Cell Cycle

Smiles

CN1CCN (CC1) C2=CC=C (C=C2) NC3=NC=C4C=C (C (=O) N (C4=N3) C5CCCC5) C#N

Molecular Formula

C24H27N7O

Additionnal Information

ON123300 is a potent and multi-targeted kinase inhibitor with IC50 of 3.9 nM, 5 nM, 26 nM, 26 nM, 9.2 nM and 11nM for CDK4, Ark5/NUAK1, PDGFRβ, FGFR1, RET (c-RET), and Fyn, respectively.

Storage Conditions

2 years -80 in solvent

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