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RSL3

Product Specifications

CAS Number

1219810-16-8

Synonyms

(1S,3R) -RSL3

Target

Ferroptosis

Applications

Apoptosis

Smiles

COC (=O) C1CC2=C (C (N1C (=O) CCl) C3=CC=C (C=C3) C (=O) OC) NC4=CC=CC=C24

Molecular Formula

C23H21ClN2O5

Additionnal Information

RSL3 ((1S,3R) -RSL3) is a ferroptosis activator in a VDAC-independent manner, exhibiting selectivity for tumor cells bearing oncogenic RAS. RSL3 binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis.

Storage Conditions

2 years -80 in solvent

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