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PD0166285

Product Specifications

CAS Number

185039-89-8

Target

Wee1

Applications

Cell Cycle

Smiles

CCN (CC) CCOC1=CC=C (C=C1) NC2=NC=C3C=C (C (=O) N (C3=N2) C) C4=C (C=CC=C4Cl) Cl

Molecular Formula

C26H27Cl2N5O2

Additionnal Information

PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations (IC50=24 nM for Wee1 and 72 nM for Myt1) . PD0166285 is also a novel G2 checkpoint abrogator. PD0166285 induces apoptosis.

Storage Conditions

2 years -80 in solvent

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