Valspodar
Product Specifications
CAS Number
121584-18-7
Synonyms
PSC 833
Target
P-gp
Applications
Neuronal Signaling
Smiles
CC=CCC (C) C (=O) C1C (=O) NC (C (=O) N (CC (=O) N (C (C (=O) NC (C (=O) N (C (C (=O) NC (C (=O) NC (C (=O) N (C (C (=O) N (C (C (=O) N (C (C (=O) N1C) C (C) C) C) CC (C) C) C) CC (C) C) C) C) C) CC (C) C) C) C (C) C) CC (C) C) C) C) C (C) C
Molecular Formula
C63H111N11O12
Additionnal Information
Valspodar is a second-generation, non-immunosuppressive inhibitor of P-glycoprotein (Pgp) that reverses multidrug resistance by blocking drug efflux. It enhances the intracellular accumulation of chemotherapeutics like mitoxantrone, restoring drug sensitivity in resistant cancer cells.
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