Pamapimod
Product Specifications
CAS Number
449811-01-2
Synonyms
R-1503, Ro4402257
Target
P38 MAPK
Applications
MAPK
Smiles
CN1C2=NC (=NC=C2C=C (C1=O) OC3=C (C=C (C=C3) F) F) NC (CCO) CCO
Molecular Formula
C19H20F2N4O4
Additionnal Information
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38gamma isoforms.
Storage Conditions
2 years -80 in solvent
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