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K03861 (AUZ454)

Product Specifications

CAS Number

853299-07-7

Target

CDK

Applications

Cell Cycle

Smiles

CN1CCN (CC1) CC2=C (C=C (C=C2) NC (=O) NC3=CC=C (C=C3) OC4=NC (=NC=C4) N) C (F) (F) F

Molecular Formula

C24H26F3N7O2

Additionnal Information

K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2 (WT), CDK2 (C118L), CDK2 (A144C), and CDK2 (C118L/A144C), respectlvely.

Storage Conditions

2 years -80 in solvent

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