Bardoxolone Methyl
Product Specifications
CAS Number
218600-53-4
Synonyms
RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me
Target
IκB/IKK
Applications
NF-κB
Smiles
CC1 (CCC2 (CCC3 (C (C2C1) C (=O) C=C4C3 (CCC5C4 (C=C (C (=O) C5 (C) C) C#N) C) C) C) C (=O) OC) C
Molecular Formula
C32H43NO4
Additionnal Information
Bardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.
Storage Conditions
2 years -80 in solvent
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