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Chaetocin

Product Specifications

CAS Number

28097-03-2

Target

Histone Methyltransferase

Applications

Epigenetics

Smiles

CN1C (=O) C23CC4 (C (N2C (=O) C1 (SS3) CO) NC5=CC=CC=C54) C67CC89C (=O) N (C (C (=O) N8C6NC1=CC=CC=C71) (SS9) CO) C

Molecular Formula

C30H28N6O6S4

Additionnal Information

Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU (VAR) 3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR) .

Storage Conditions

2 years -80 in solvent

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