Pacritinib
Product Specifications
CAS Number
937272-79-2
Synonyms
SB1518
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
C1CCN (C1) CCOC2=C3COCC=CCOCC4=CC (=CC=C4) C5=NC (=NC=C5) NC (=C3) C=C2
Molecular Formula
C28H32N4O3
Additionnal Information
Pacritinib is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent
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