Tubastatin A
Product Specifications
CAS Number
1252003-15-8
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CN1CCC2=C (C1) C3=CC=CC=C3N2CC4=CC=C (C=C4) C (=O) NO
Molecular Formula
C20H21N3O2
Additionnal Information
Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold) . Tubastatin A promotes autophagy and increases apoptosis.
Storage Conditions
2 years -80 in solvent
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