GDC-0349

Product Specifications

CAS Number

1207360-89-1

Synonyms

RG-7603

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CCNC (=O) NC1=CC=C (C=C1) C2=NC3=C (CCN (C3) C4COC4) C (=N2) N5CCOCC5C

Molecular Formula

C24H32N6O3

Additionnal Information

GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.

Storage Conditions

2 years -80 in solvent

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