Necrostatin-1
Product Specifications
CAS Number
4311-88-0
Synonyms
Nec-1
Target
TNF-alpha
Applications
Apoptosis
Smiles
CN1C (=O) C (NC1=S) CC2=CNC3=CC=CC=C32
Molecular Formula
C13H13N3OS
Additionnal Information
Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells. Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2027103 1.0 µg DNA
RPS12P28 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 