Necrostatin-1
Product Specifications
CAS Number
4311-88-0
Synonyms
Nec-1
Target
TNF-alpha
Applications
Apoptosis
Smiles
CN1C (=O) C (NC1=S) CC2=CNC3=CC=CC=C32
Molecular Formula
C13H13N3OS
Additionnal Information
Necrostatin-1 (Nec-1) is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells. Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis.
Storage Conditions
2 years -80 in solvent
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