Nirogacestat (PF-03084014)
Product Specifications
CAS Number
1290543-63-3
Synonyms
PF-3084014
Target
Apoptosis related
Applications
Apoptosis
Smiles
CCCC (C (=O) NC1=CN (C=N1) C (C) (C) CNCC (C) (C) C) NC2CCC3=C (C2) C (=CC (=C3) F) F
Molecular Formula
C27H41F2N5O
Additionnal Information
Nirogacestat (PF-03084014, PF-3084014) is a selective gamma-secretase inhibitor with IC50 of 6.2 nM in a cell-free assay. Nirogacestat (PF-03084014, PF-3084014) induces apoptosis. Phase 2.
Storage Conditions
2 years -80 in solvent
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