VE-821
Product Specifications
CAS Number
1232410-49-9
Synonyms
ATR inhibitor IV
Target
ATM/ATR
Applications
PI3K/Akt/mTOR
Smiles
CS (=O) (=O) C1=CC=C (C=C1) C2=CN=C (C (=N2) C (=O) NC3=CC=CC=C3) N
Molecular Formula
C18H16N4O3S
Additionnal Information
VE-821 (ATR inhibitor IV) is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays, shows inhibition of H2AX phosphorylation, minimal activity against PIKKs ATM, DNA-PK, mTOR and PI3Kγ.
Storage Conditions
2 years -80 in solvent
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