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GSK864

Product Specifications

CAS Number

1816331-66-4

Target

Dehydrogenase

Applications

Metabolism

Molecular Formula

C30H31FN6O4

Additionnal Information

GSK864 is a cell-penetrant, potent, and selective inhibitor of isocitrate dehydrogenase 1 (IDH1) mutants, specifically targeting the R132C, R132H, and R132G variants with IC50 values of 8.8 nM, 15.2 nM, and 16.6 nM, respectively.

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