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Zorifertinib (AZD3759)

Product Specifications

CAS Number

1626387-80-1

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1CN (CCN1C (=O) OC2=C (C=C3C (=C2) C (=NC=N3) NC4=C (C (=CC=C4) Cl) F) OC) C

Molecular Formula

C22H23ClFN5O3

Additionnal Information

Zorifertinib (AZD3759) is a potent, oral active, CNS-penetrant EGFR inhibitor with IC50 of 0.3 nM, 0.2 nM, and 0.2 nM for EGFR (WT), EGFR (L858R), and EGFR (exon 19Del), respectively. Phase 1.

Storage Conditions

2 years -80 in solvent

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