Zorifertinib (AZD3759)
Product Specifications
CAS Number
1626387-80-1
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1CN (CCN1C (=O) OC2=C (C=C3C (=C2) C (=NC=N3) NC4=C (C (=CC=C4) Cl) F) OC) C
Molecular Formula
C22H23ClFN5O3
Additionnal Information
Zorifertinib (AZD3759) is a potent, oral active, CNS-penetrant EGFR inhibitor with IC50 of 0.3 nM, 0.2 nM, and 0.2 nM for EGFR (WT), EGFR (L858R), and EGFR (exon 19Del), respectively. Phase 1.
Storage Conditions
2 years -80 in solvent
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