THZ2
Product Specifications
CAS Number
1604810-84-5
Target
CDK
Applications
Cell Cycle
Smiles
CN (C) CC=CC (=O) NC1=CC=CC (=C1) C (=O) NC2=CC=CC (=C2) NC3=NC=C (C (=N3) C4=CNC5=CC=CC=C54) Cl
Molecular Formula
C31H28ClN7O2
Additionnal Information
THZ2, a THZ1 analog, is a selective inhibitor of CDK7 with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM.
Storage Conditions
3 years -20°C powder
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