PLX7904
Product Specifications
CAS Number
1393465-84-3
Synonyms
PB04
Target
Raf
Applications
MAPK
Smiles
CCN (C) S (=O) (=O) NC1=C (C (=C (C=C1) F) C (=O) C2=CNC3=C2C=C (C=N3) C4=CN=C (N=C4) C5CC5) F
Molecular Formula
C24H22F2N6O3S
Additionnal Information
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.
Storage Conditions
2 years -80 in solvent
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