Bioymifi
Product Specifications
CAS Number
1420071-30-2
Target
TNF-alpha
Applications
Apoptosis
Smiles
C1=CC (=CC=C1N2C (=O) C (=CC3=CC=C (O3) C4=CC5=C (C=C4) C (=O) NC5=O) SC2=N) Br
Molecular Formula
C22H12BrN3O4S
Additionnal Information
Bioymifi, a small-molecule death receptor 5 (DR5) agonist, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM but showed little binding affinity to the DR4 ECD. It induces DR5 clustering and aggregation, leading to apoptosis.
Storage Conditions
2 years -80 in solvent
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