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Belumosudil (KD025)

Product Specifications

CAS Number

911417-87-3

Synonyms

SLx-2119

Target

ROCK

Applications

Cytoskeletal Signaling

Smiles

CC (C) NC (=O) COC1=CC=CC (=C1) C2=NC3=CC=CC=C3C (=N2) NC4=CC5=C (C=C4) NN=C5

Molecular Formula

C26H24N6O2

Additionnal Information

Belumosudil (KD025, SLx-2119) is an orally available, and selective ROCK2 inhibitor with IC50 and Ki of 60 nM and 41 nM, respectively. Phase 2.

Storage Conditions

2 years -80 in solvent

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