Belumosudil (KD025)
Product Specifications
CAS Number
911417-87-3
Synonyms
SLx-2119
Target
ROCK
Applications
Cytoskeletal Signaling
Smiles
CC (C) NC (=O) COC1=CC=CC (=C1) C2=NC3=CC=CC=C3C (=N2) NC4=CC5=C (C=C4) NN=C5
Molecular Formula
C26H24N6O2
Additionnal Information
Belumosudil (KD025, SLx-2119) is an orally available, and selective ROCK2 inhibitor with IC50 and Ki of 60 nM and 41 nM, respectively. Phase 2.
Storage Conditions
2 years -80 in solvent
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