Avadomide (CC-122)
Product Specifications
CAS Number
1015474-32-4
Target
E3 Ligase
Applications
Ubiquitin
Smiles
CC1=NC2=CC=CC (=C2C (=O) N1C3CCC (=O) NC3=O) N
Molecular Formula
C14H14N4O3
Additionnal Information
Avadomide (CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma (DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.
Storage Conditions
2 years -80 in solvent
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