Xanthohumol

Product Specifications

CAS Number

6754-58-1

Target

COX

Applications

Neuronal Signaling

Smiles

CC (=CCC1=C (C (=C (C=C1O) OC) C (=O) C=CC2=CC=C (C=C2) O) O) C

Molecular Formula

C21H22O5

Additionnal Information

Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 μM. Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses. Xanthohumol induces growth inhibition and apoptosis in cancer cells. Phase 1.